You are here

Home › Research › Publications ›

ClonoCalc and ClonoPlot: immune repertoire analysis from raw files to publication figures with graphical user interface

TitleClonoCalc and ClonoPlot: immune repertoire analysis from raw files to publication figures with graphical user interface
Publication TypeJournal Article
Year of Publication2017
AuthorsFähnrich, A, Krebbel, M, Decker, N, Leucker, M, Lange, FD, Kalies, K, Möller, S
JournalBMC Bioinformatics
Volume18
Pagination164
ISSN1471-2105
Abstract

Next generation sequencing (NGS) technologies enable studies and analyses of the diversity of both T and B cell receptors (TCR and BCR) in human and animal systems to elucidate immune functions in health and disease. Over the last few years, several algorithms and tools have been developed to support respective analyses of raw sequencing data of the immune repertoire. These tools focus on distinct aspects of the data processing and require a strong bioinformatics background. To facilitate the analysis of T and B cell repertoires by less experienced users, software is needed that combines the most common tools for repertoire analysis.
URLhttp://dx.doi.org/10.1186/s12859-017-1575-2
DOI10.1186/s12859-017-1575-2
Bibtex: 
@article {1258,
	title = {ClonoCalc and ClonoPlot: immune repertoire analysis from raw files to publication figures with graphical user interface},
	journal = {BMC Bioinformatics},
	volume = {18},
	year = {2017},
	pages = {164},
	abstract = {<p>Next generation sequencing (NGS) technologies enable studies and analyses of the diversity of both T and B cell receptors (TCR and BCR) in human and animal systems to elucidate immune functions in health and disease. Over the last few years, several algorithms and tools have been developed to support respective analyses of raw sequencing data of the immune repertoire. These tools focus on distinct aspects of the data processing and require a strong bioinformatics background. To facilitate the analysis of T and B cell repertoires by less experienced users, software is needed that combines the most common tools for repertoire analysis.</p>
},
	issn = {1471-2105},
	doi = {10.1186/s12859-017-1575-2},
	url = {http://dx.doi.org/10.1186/s12859-017-1575-2},
	author = {Anke F{\"a}hnrich and Moritz Krebbel and Normann Decker and Martin Leucker and Felix D. Lange and Kathrin Kalies and Steffen M{\"o}ller}
}